Obstetrics and gynecology encompasses the vital care of women's health throughout life, from reproductive wellness and pregnancy to menopause and beyond. This dynamic field explores the complex biological processes of childbirth, the prevention of diseases affecting female reproductive organs, and the latest advancements in maternal safety. It is a discipline deeply rooted in both immediate clinical impact and long-term public health strategies.

On Gist.Science, we continuously monitor medRxiv for the newest preprints in this category, ensuring you have instant access to cutting-edge research before formal publication. Our team processes every new submission to provide both detailed technical summaries and clear, plain-language explanations, making these complex studies understandable for everyone from specialists to curious readers.

Below are the latest papers in obstetrics and gynecology, offering fresh insights into the future of women's healthcare.

📄 obstetrics and gynecology

Temporal trends in preterm birth rate over the last 30 years in Sweden: a population-based study

This population-based study of over 3.2 million Swedish pregnancies reveals that while preterm birth rates remained stable from 1991 to 2005, they significantly declined from 2006 to 2021 due to a reduction in spontaneous preterm births, particularly among late and moderately preterm categories, despite the absence of a nationwide preventive strategy.

Han, B., Sundelin, H., Ytterberg, K., Juodakis, J., Nyeboe, P., Rosengren, A., Stromberg, U., Norman, M., Svanvik, T., S (…)2026-02-26
📄 obstetrics and gynecology

Impact of Preterm Premature Rupture of Membranes on Composite Adverse Perinatal Outcomes and Associated Predictors Among Pregnant Women in Tigray, Northern Ethiopia: A Prospective Cohort Study

This prospective cohort study in Tigray, Northern Ethiopia, demonstrates that preterm premature rupture of membranes (PPROM) significantly increases the risk of composite adverse perinatal outcomes, with independent predictors including prior pregnancy infections, lack of iron-folate supplementation, pelvic pain, and a latency period of 1–3 days.

Welesamuel, G. T., Araya, A., Nega, G., Alem, B., Guesh, T., Mekonene, H., Abadi, F., Gebreluel, H., Asres, N., Haile, T (…)2026-02-24
📄 obstetrics and gynecology

Maternal Willingness to Participate in Research Involving Neuroimaging, Biological Sample Collection, and Data Storage: Towards a Multicentre Neurodevelopmental Research in a low-resource setting

This study of 300 mothers in a low-resource setting reveals high overall willingness to participate in neurodevelopmental research involving brain imaging and routine biospecimens, though acceptance varies significantly by sample type and is influenced by socioeconomic factors, highlighting the need for tailored strategies to ensure equitable engagement.

Piersson, A. D., Amartey, C., Quartei, S. T., Dzefi-Tettey, K., Sefogah, P. E., Lopez, A. R.2026-02-24
📄 obstetrics and gynecology

Unmet Health Needs In Namanve Industrial Park

This qualitative study conducted in Namanve Industrial Park, Uganda, identifies that unmet health needs among workers and residents are primarily driven by systemic gaps in preventive services, essential commodities, WASH infrastructure, and mental health support, necessitating integrated interventions that combine health education with improved service delivery and structural improvements.

justus, a., Emmanuel, K., Kavuma, P. D., Alone, K., Achiro, S.2026-02-18
📄 obstetrics and gynecology

Protocol for a prospective accuracy study on an artificial intelligence-based ultrasound system for gestational age estimation among pregnant women in Ghana, Kenya and South Africa

This study protocol outlines a multi-country prospective cohort study in Ghana, Kenya, and South Africa designed to validate the accuracy of an AI-based handheld ultrasound system for gestational age estimation against conventional fetal biometry, aiming to support pre-eclampsia risk screening and the design of the PEARLS trial in low-resource settings.

Swarray-Deen, A., McDougall, A., Chemway, R., Craik, R., Jayaratnam, S., Joseph, N., Mahar, R. K., Koye, D. N., Nguyen (…)2026-02-15
📄 obstetrics and gynecology

Causal effect of gut Streptococcus on maternal genitourinary infection during pregnancy: evidence from Mendelian randomization analysis

This Mendelian randomization study provides genetic evidence that higher abundance of gut Streptococcus causally reduces the risk of maternal genitourinary infections during pregnancy through a localized mechanism independent of systemic inflammation or major adverse pregnancy outcomes.

Wu, R., Baoyin, B., Badarch, J., Tsagaankhuu, S., Jiang, X., Chen, J., Boldbaatar, D.2026-02-02
📄 obstetrics and gynecology

Correlates of obstetric violence by maternity care providers during antenatal consultations and childbirth in two referral hospitals in Bafoussam (West-Cameroon)

A hospital-based survey in Bafoussam, Cameroon, reveals that obstetric violence is highly prevalent during childbirth (54.7%) and antenatal care (8.1%), with financial inability to pay for services identified as a significant risk factor for both.

Alima, J. M., Ikei, S. A., FOUOGUE, J. T., Tamo, Y. F., Fouedjio, H. J., Kenfack, B.2026-01-24
📄 obstetrics and gynecology

Preterm premature rupture of membranes before 32 weeks of gestation:Management and pregnancy outcomes

This retrospective bicentric study demonstrates that in pregnancies complicated by preterm premature rupture of membranes between 22 and 32 weeks, neonatal survival and morbidity are significantly better in the 26–32 week group compared to the 22–26 week group, with gestational age at rupture and delivery, birth weight, Apgar score, and amniotic fluid volume identified as critical determinants of prognosis.

BEN NECIB, T., BOUMAIZA, A., GARCI, M., MAKNI, M., ABDELJABBAR, A., CHAOUACHI, A., SLIMANI, O., MATHLOUTHI, N., BELGHITH (…)2026-01-21
📄 obstetrics and gynecology

Quetiapine in a Low Dosage During Pregnancy: Neonatal Outcomes in a Retrospective Cohort Study

This retrospective single-center study of 30 neonates in the Netherlands suggests an association between maternal low-dose quetiapine use during pregnancy and relatively high rates of preterm birth, small-for-gestational-age status, and NICU admissions, though the authors caution that these findings require validation through larger, controlled prospective studies.

van Tienoven, S. F. J., Gossink, F., Dullemond, R., van Dillen, J.2026-01-21